In this paper, we have analyzed the performance of downlink multiuser six generation (6G) and beyond 5G (B5G) with concurrently different data transmission compatible MIMO-NOMA wireless communication system. The proposed simulated system has been implemented incorporating ML decoding based QR channel decomposition aided successive interference cancellation (SIC) scheme signal detection, convolutional channel coding, BPSK, and QAM digital modulation schemes. Two different types of messages are transmitted simultaneously from the base station (BS) through a 2× 2 MIMO channel for two different users. The image data is transmitted for user one and synthetic data is used for the other user. By observing the simulation results, we can say that the system provides acceptable performance under AWGN and Rayleigh fading channels. To improve the performance, we have properly assigned power to the users, and accurately maintained the signal’s phase difference between the users. With the increase of the signal-to-noise ratio (SNR) the bit error rate (BER) has degraded adequately which indicates the system is very robust and efficient for the transmission of different data concurrently and suitable for the next generation of wireless communications.