Pharmacotherapy against oxidative stress in chronic kidney disease: Promising small molecule natural products targeting nrf2-ho-1 signaling
The global burden of chronic kidney disease (CKD) intertwined with cardiovascular disease
has become a major health problem. Oxidative stress (OS) plays an important role in the
pathophysiology of CKD. The nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant
responsive element (ARE) antioxidant system plays a critical role in kidney protection by
regulating antioxidants during OS. Heme oxygenase-1 (HO-1), one of the targets of Nrf2-
ARE, plays an important role in regulating OS and is protective in a variety of human and …
has become a major health problem. Oxidative stress (OS) plays an important role in the
pathophysiology of CKD. The nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant
responsive element (ARE) antioxidant system plays a critical role in kidney protection by
regulating antioxidants during OS. Heme oxygenase-1 (HO-1), one of the targets of Nrf2-
ARE, plays an important role in regulating OS and is protective in a variety of human and …
[PDF][PDF] A.; Ha, H. Pharmacotherapy against Oxidative Stress in Chronic Kidney Disease: Promising Small Molecule Natural Products Targeting Nrf2-HO-1 Signaling …
MJ Uddin, EH Kim, M Hannan - 2021 - pdfs.semanticscholar.org
The global burden of chronic kidney disease (CKD) intertwined with cardiovascular disease
has become a major health problem. Oxidative stress (OS) plays an important role in the
pathophysiology of CKD. The nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant
responsive element (ARE) antioxidant system plays a critical role in kidney protection by
regulating antioxidants during OS. Heme oxygenase-1 (HO-1), one of the targets of Nrf2-
ARE, plays an important role in regulating OS and is protective in a variety of human and …
has become a major health problem. Oxidative stress (OS) plays an important role in the
pathophysiology of CKD. The nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant
responsive element (ARE) antioxidant system plays a critical role in kidney protection by
regulating antioxidants during OS. Heme oxygenase-1 (HO-1), one of the targets of Nrf2-
ARE, plays an important role in regulating OS and is protective in a variety of human and …
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