Phase-transfer Catalysis (PTC) can increase yields, reduce cycle times, eliminate hazardous
or expensive reagents and solvents, and provide numerous other benefits to organic
chemical manufacturers, so that much effort has been directed toward the coupling of phase-
transfer catalysis with asymmetric synthesis. There are hundreds of industrial applications of
PTC for a variety of processes of organic synthesis and major advantages of PTC in
industrial applications; which easily recognized in the given examples. Also, many synthetic …

The field of phase transfer catalysis is a tribute to the chemists involved in process
development research. Phase transfer catalysis is a solution to numerous cost and yield
problems encountered regularly in industrial laboratories. In fact, much of the early work in
this area was conducted by industrial chemists although the work was not labelled phase
transfer catalysis at the time. We certainly do not intend to minimize the contributions of
academic chemists to this field, but it is an unalterable fact that much of the early …