Photochemically activated carbon monoxide release for biological targets. Toward developing air-stable photoCORMs labilized by visible light

RD Rimmer, AE Pierri, PC Ford - Coordination Chemistry Reviews, 2012 - Elsevier
RD Rimmer, AE Pierri, PC Ford
Coordination Chemistry Reviews, 2012Elsevier
The potential therapeutic effects of carbon monoxide in several disease states, and new
methodologies for CO delivery to specific targets is a topic of growing interest in mammalian
physiology. Here we provide an overview of recent efforts in this laboratory regarding
several types of carbonyl complexes of the group 6 metal and of those in other laboratories
that are focused on developing photochemical techniques for such CO delivery. Photo-
activated carbon monoxide releasing moieties (photoCORMs) based on manganese, iron …
The potential therapeutic effects of carbon monoxide in several disease states, and new methodologies for CO delivery to specific targets is a topic of growing interest in mammalian physiology. Here we provide an overview of recent efforts in this laboratory regarding several types of carbonyl complexes of the group 6 metal and of those in other laboratories that are focused on developing photochemical techniques for such CO delivery. Photo-activated carbon monoxide releasing moieties (photoCORMs) based on manganese, iron and group 6 metals are described.
Elsevier
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