The cell nucleus is three-dimensionally and dynamically organized by nuclear components
with high molecular density, such as chromatin and nuclear bodies. The structure and
functions of these components are represented by the diffusion and interaction of related
factors. Recent studies suggest that the nucleolus can be assessed using various protein
probes, as the probes are highly mobile in this organelle, although it is known that they have
a densely packed structure. However, physicochemical properties of the nucleolus itself …