Von Willebrand factor (vWF) is glycoprotein crucial to primary … intrinsic coagulation cascade,
through factor VIII stabilization. It … vWF is named after the physician Erik von Willebrand, who …

… , which broadens prospective studies on the physiological and pathophysiological impact of
VWF … Shear-induced interaction of platelets with von Willebrand factor results in glycoprotein …

… (VWF) deficiency, either quantitative or qualitative, results in von Willebrand disease (VWD), …
on the role of the Von Willebrand Factor (VWF) VWF-FVIII interaction in vascular physiology. …

… In physiologic conditions, the tethering of flowing platelets to immobilized VWF contributes
to initiating hemostasis, the process that arrests hemorrhage after tissue trauma. In diseased …

… Structural specialisations enable von Willebrand factor (VWF) to assemble during …
Elongational flow induces the unfolding of von Willebrand factor at physiological flow rates. …

… blood flow with high shear stress, as in capillaries under physiologic … The biologicalfunction
of von Willebrand antigen II after cleavage … is that the latter appear to lack a physiological …

… However, von Willebrand factor (VWF), with help from … in von Willebrand disease contribute
to and are illuminated by VWF biology. I attempt to integrate classic studies on the physiology …

Von Willebrand factor (VWF) is a blood glycoprotein that is required for normal hemostasis,
and deficiency of VWF, or von Willebrand disease (VWD), is the most common inherited …

… of blood clotting from the molecular to the physiological level, and provide new physical …
physiological level, with a large focus on the large multimeric protein von Willebrand Factor (…

… After a description of the structure and physiology of VWF, all these aspects are discussed
… Structure and function of von Willebrand factor Von Willebrand factor is a large multimeric …