Phytochemicals and their impact on adipose tissue inflammation and diabetes

A Leiherer, A Mündlein, H Drexel - Vascular pharmacology, 2013 - Elsevier
Type 2 diabetes mellitus is an inflammatory disease and the mechanisms that underlie this
disease, although still incompletely understood, take place in the adipose tissue of obese
subjects. Concurrently, the prevalence of obesity caused by Western diet's excessive energy
intake and the lack of exercise escalates, and is believed to be causative for the chronic
inflammatory state in adipose tissue. Overnutrition itself as an overload of energy may
induce the adipocytes to secrete chemokines activating and attracting immune cells to …
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