Pituitary apoplexy in pregnancy: a case series and literature review
S Grand'Maison, F Weber, MJ Bédard… - Obstetric …, 2015 - journals.sagepub.com
S Grand'Maison, F Weber, MJ Bédard, M Mahone, A Godbout
Obstetric Medicine, 2015•journals.sagepub.comBackground Severe headache during pregnancy is a challenging condition that may rarely
imply endocrine disturbances. Rapid recognition of pituitary apoplexy is needed to improve
pregnancy outcome. Objective To review and compare maternal and fetal outcomes after
pituitary apoplexy. Methods Four cases of pituitary apoplexy during pregnancy in our centre
are reported and literature review covering the past 54 years was performed. Results In the
four cases presented and the 33 reported in the literature, most women presented with …
imply endocrine disturbances. Rapid recognition of pituitary apoplexy is needed to improve
pregnancy outcome. Objective To review and compare maternal and fetal outcomes after
pituitary apoplexy. Methods Four cases of pituitary apoplexy during pregnancy in our centre
are reported and literature review covering the past 54 years was performed. Results In the
four cases presented and the 33 reported in the literature, most women presented with …
Background
Severe headache during pregnancy is a challenging condition that may rarely imply endocrine disturbances. Rapid recognition of pituitary apoplexy is needed to improve pregnancy outcome.
Objective
To review and compare maternal and fetal outcomes after pituitary apoplexy.
Methods
Four cases of pituitary apoplexy during pregnancy in our centre are reported and literature review covering the past 54 years was performed.
Results
In the four cases presented and the 33 reported in the literature, most women presented with severe headaches and systemic symptoms. Overall, 42% were treated surgically, 31% received bromocriptine or cabergoline and 61% were given hormone replacement. No major obstetrical complication was reported and all babies were healthy.
Conclusion
Pituitary apoplexy is a rare cause of sudden and severe headache during pregnancy. Rapid identification of this condition with potentially associated endocrine disturbances is important to ensure maternal and fetal well-being. A multidisciplinary team approach seems to reduce morbidity and mortality.
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