Plasma creatinine rises dramatically in the first 48 hours of life in preterm infants

LS Miall, MJ Henderson, AJ Turner, KG Brownlee… - …, 1999 - publications.aap.org
Objective. Published data show that plasma creatinine falls steadily during the first 28 days
of life and that creatinine levels in the neonatal period are higher in more premature infants.
However, the best reference data commence on day 2 of life. The objective of this study was
to document how plasma creatinine changes in the first 48 hours of life and to examine the
reason for the apparently high levels of creatinine in preterm infants, compared with
maternal levels. Design. A prospective observational study on a regional neonatal intensive …
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