Platelet-rich plasma versus CROSS technique with 100% trichloroacetic acid versus combined skin needling and platelet rich plasma in the treatment of atrophic acne …

E Nofal, A Helmy, A Nofal, R Alakad… - Dermatologic Surgery, 2014 - journals.lww.com
E Nofal, A Helmy, A Nofal, R Alakad, M Nasr
Dermatologic Surgery, 2014journals.lww.com
BACKGROUND Platelet-rich plasma (PRP) is an autologous preparation of platelets in
concentrated plasma that may be beneficial in the treatment of atrophic acne scars by
promoting collagen deposition. Skin needling is a technique that uses a sterile dermaroller
to puncture the skin and release growth factors. The combination of skin needling and PRP
could enhance the efficacy of both modalities. Chemical reconstruction of skin scars
technique consists of focal application of high concentration of trichloroacetic acid (TCA) on …
Abstract
BACKGROUND
Platelet-rich plasma (PRP) is an autologous preparation of platelets in concentrated plasma that may be beneficial in the treatment of atrophic acne scars by promoting collagen deposition. Skin needling is a technique that uses a sterile dermaroller to puncture the skin and release growth factors. The combination of skin needling and PRP could enhance the efficacy of both modalities. Chemical reconstruction of skin scars technique consists of focal application of high concentration of trichloroacetic acid (TCA) on the acne scars to stimulate collagen production.
OBJECTIVE
To evaluate the efficacy and safety of intradermal injection of PRP, 100% focal TCA, and combined skin needling plus topical PRP in the treatment of atrophic acne scars.
Lippincott Williams & Wilkins
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