Polymorphisms in Long Noncoding RNA H19 Contribute to the Protective Effects of Coal Workers' Pneumoconiosis in a Chinese Population
Q Wu, W Yan, R Han, J Yang, J Yuan, X Ji… - International Journal of …, 2016 - mdpi.com
The H19 is a kind of long noncoding RNA, which has been implicated in multiple biological
functions. However, the associations between genetic variants in H19 and susceptibility of
coal workers' pneumoconiosis (CWP) have been seldom reported. In the present study,
three potential polymorphisms (rs2067051, rs217727, and rs2839702) in H19 were
genotyped in a case-control study including 703 CWP cases and 705 controls. We found
that individuals with the H19 rs2067051 CT/TT genotypes showed a decreased risk of CWP …
functions. However, the associations between genetic variants in H19 and susceptibility of
coal workers' pneumoconiosis (CWP) have been seldom reported. In the present study,
three potential polymorphisms (rs2067051, rs217727, and rs2839702) in H19 were
genotyped in a case-control study including 703 CWP cases and 705 controls. We found
that individuals with the H19 rs2067051 CT/TT genotypes showed a decreased risk of CWP …
Polymorphisms in long noncoding RNA H19 contribute to the protective effects of coal workers' pneumoconiosis in a Chinese population.
WQY Wu QiuYun, YWW Yan WeiWen, HRH Han RuHui… - 2016 - cabidigitallibrary.org
The H19 is a kind of long noncoding RNA, which has been implicated in multiple biological
functions. However, the associations between genetic variants in H19 and susceptibility of
coal workers' pneumoconiosis (CWP) have been seldom reported. In the present study,
three potential polymorphisms (rs2067051, rs217727, and rs2839702) in H19 were
genotyped in a case-control study including 703 CWP cases and 705 controls. We found
that individuals with the H19 rs2067051 CT/TT genotypes showed a decreased risk of CWP …
functions. However, the associations between genetic variants in H19 and susceptibility of
coal workers' pneumoconiosis (CWP) have been seldom reported. In the present study,
three potential polymorphisms (rs2067051, rs217727, and rs2839702) in H19 were
genotyped in a case-control study including 703 CWP cases and 705 controls. We found
that individuals with the H19 rs2067051 CT/TT genotypes showed a decreased risk of CWP …
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