characterized by endoplasmic reticulum (ER) stress with subsequent development of liver
disease. Our aim was to estimate the frequency of hemochromatosis gene (HFE) mutant
alleles (C282Y and H63D) and alpha-1 antitrypsin S/Z variants among Egyptian HCV
cirrhotic patients and in hepatocellular carcinoma patients and to evaluate their effects on
disease progression. HFE and alpha-1 antitrypsin polymorphisms were characterized in 200 …