Polyoxometalates as antitumor agents: bioactivity of a new polyoxometalate with copper on a human osteosarcoma model
IE Leon, V Porro, S Astrada, MG Egusquiza… - Chemico-biological …, 2014 - Elsevier
Polyoxometalates (POMs) are early transition metal oxygen anion clusters. They display
interesting biological effects mainly related to their antiviral and antitumor properties. On the
other hand, copper compounds also show different biological and pharmacological effects in
cell culture and in animal models. We report herein for the first time, a detailed study of the
mechanisms of action of a copper (II) compound of the group of HPOMs with the formula K 7
Na 3 [Cu 4 (H 2 O) 2 (PW 9 0 34) 2] 20H 2 O (PW 9 Cu), in a model of human osteosarcoma …
interesting biological effects mainly related to their antiviral and antitumor properties. On the
other hand, copper compounds also show different biological and pharmacological effects in
cell culture and in animal models. We report herein for the first time, a detailed study of the
mechanisms of action of a copper (II) compound of the group of HPOMs with the formula K 7
Na 3 [Cu 4 (H 2 O) 2 (PW 9 0 34) 2] 20H 2 O (PW 9 Cu), in a model of human osteosarcoma …
以上显示的是最相近的搜索结果。 查看全部搜索结果