Background Recent survivals of our pig-to-baboon kidney xenotransplants have been
markedly shorter than the graft survivals we previously reported. The discovery of high levels
of porcine cytomegalovirus (pCMV) in one of the rejected xenografts led us to evaluate
whether this reduction in graft survival might be because of the inadvertent introduction of
pCMV into our α1, 3-galactosyltransferase gene knockout swine herd. Methods Archived
frozen sections of xeno-kidney grafts over the past 10 years were analyzed for the presence …

… Porcine cytomegalovirus infection is associated with early rejection of kidney grafts in a
pig to baboon xenotransplantation model. Transplantation 2014; 98: 411. … Related Videos …
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