Melanopsin-containing retinal ganglion cells have recently been shown highly relevant to
the non-image forming effects of light, through their direct projections on brain circuits that
regulate alertness, mood and circadian rhythms. A quantitative assessment of functionality of
the melanopsin-signaling pathway could be highly relevant in order to mechanistically
understand individual differences in the effects of light on these regulatory systems. We here
propose and validate a reliable quantification of the melanopsin-dependent Post …