complexity resembles that of humans in structure and tissue components; however, axolotl
limbs develop postembryonically. In this work, we evaluated the postembryonic
development of the appendicular skeleton and its changes with aging. Results The juvenile
limb skeleton is formed mostly by Sox9/Col1a2 cartilage cells. Ossification of the
appendicular skeleton starts when animals reach a length of 10 cm, and cartilage cells are …