Postembryonic development and aging of the appendicular skeleton in Ambystoma mexicanum

C Riquelme‐Guzmán, M Schuez, A Böhm… - Developmental …, 2022 - Wiley Online Library
Background The axolotl is a key model to study appendicular regeneration. The limb
complexity resembles that of humans in structure and tissue components; however, axolotl
limbs develop postembryonically. In this work, we evaluated the postembryonic
development of the appendicular skeleton and its changes with aging. Results The juvenile
limb skeleton is formed mostly by Sox9/Col1a2 cartilage cells. Ossification of the
appendicular skeleton starts when animals reach a length of 10 cm, and cartilage cells are …

Postembryonic development and aging of the appendicular skeleton in Ambystoma mexicanum

C Riquelme‐Guzmán… - …, 2021 - nottingham-repository.worktribe.com
Background The axolotl is a key model to study appendicular regeneration. The limb
complexity resembles that of humans in structure and tissue components; however, axolotl
limbs develop postembryonically. In this work, we evaluated the postembryonic
development of the appendicular skeleton and its changes with aging. Results The juvenile
limb skeleton is formed mostly by Sox9/Col1a2 cartilage cells. Ossification of the
appendicular skeleton starts when animals reach a length of 10 cm, and cartilage cells are …
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