Predicting optimal deep brain stimulation parameters for Parkinson's disease using functional MRI and machine learning

…, A Loh, SK Kalia, M Hodaie, B Li, S Prasad… - Nature …, 2021 - nature.com
functional magnetic resonance imaging (fMRI) can be used to predict optimal stimulation
settings for … trial in 67 PD patients using optimal and non-optimal stimulation settings. Clinically …

Toward on-demand deep brain stimulation using online Parkinson's disease prediction driven by dynamic detection

A Mohammed, M Zamani, R Bayford… - … Neural Systems and …, 2017 - ieeexplore.ieee.org
… adjust stimulation parameters by the brain response in real time. The optimum combination
… odd degree polynomials are tested since the parameter e in the logistic function fLR(x) in (10…

[HTML][HTML] Neuronal oscillations predict deep brain stimulation outcome in Parkinson's disease

J Hirschmann, A Steina, J Vesper, E Florin, A Schnitzler - Brain Stimulation, 2022 - Elsevier
… about the optimal location, time and intensity of stimulation. … disorder specialist following
optimization of DBS parameters. In … as a function of number of features for the prediction of DBS …

… and fMRI-based Pipeline for Optimization of Deep Brain Stimulation During Parkinson's Disease Treatment: Towards Rapid Semi-automated Stimulation Optimization

J Qiu, J Karigiannis, B Santyr, A Loh… - … in Health and …, 2024 - ieeexplore.ieee.org
… of optimal DBS parameters in classification task, and the predicted optimal DBS parameter
value in prediction … For the classification model, a sigmoid activation function was employed at …

Machine learning explains response variability of deep brain stimulation on Parkinson's disease quality of life

E Ferrea, F Negahbani, I Cebi, D Weiss… - npj Digital …, 2024 - nature.com
… To obtain the best experience, we recommend you use a … the data processing and predictive
modeling, we use SHAP (… mean Shapley value, using the ‘ols’ function from the ‘statsmodels.…

Value of subthalamic nucleus local field potentials recordings in predicting stimulation parameters for deep brain stimulation in Parkinson's disease

F Yoshida, I Martinez-Torres, A Pogosyan… - Journal of Neurology …, 2010 - jnnp.bmj.com
functional localisation of the STN by online spectral analysis of LFPs recorded from the DBS
electrode may provide information that helps predict optimal stimulation settingsfunctional

Machine learning approach to optimizing combined stimulation and medication therapies for Parkinson's disease

RR Shamir, T Dolber, AM Noecker, BL Walter… - Brain stimulation, 2015 - Elsevier
Deep brain stimulation (DBS) of the subthalamic region is an … extends the typical clinical
database functionality, as well as … Our goal was to use computer optimization to predict the most …

Machine learning prediction of motor response after deep brain stimulation in Parkinson's disease

J Habets, A Duits, L Sijben, B De Greef, A Mulders… - Medrxiv, 2019 - medrxiv.org
… Postoperative stimulation parameters and dopaminergic … Our prediction model performs
with an average area under the … better and worse neuropsychological functioning, respectively. …

Combining multimodal biomarkers to guide deep brain stimulation programming in Parkinson disease

A Shah, TAK Nguyen, K Peterman, S Khawaldeh… - … : technology at the …, 2023 - Elsevier
… in Movement Disorder Society Unified Parkinsons Disease … , average, and minimum likelihoods
of predicting the optimal … by stimulation field modeling combined with functional anatomy…

Resting state functional MRI in Parkinson's disease: the impact of deep brain stimulation on 'effective'connectivity

J Kahan, M Urner, R Moran, G Flandin, A Marreiros… - Brain, 2014 - academic.oup.com
… nucleus predicted clinical status and therapeutic response to deep brain stimulation; however,
Stimulation parameters were set to produce optimal clinical responses. Medication was …