the rapid, efficient, and long-term expansion of healthy human oral mucosa and head and
neck squamous cell carcinoma (HNSCC) tumor organoids. The HNSCC tumor organoids
provide a functional platform for analyzing tumor cell phenotype, tumorigenic potential, and
drug and radiotherapy response, and they have a potential role in clinical decision-making.
See related article by Driehuis et al., p. 852.