Prenatal exposure to integerrimine N-oxide enriched butanolic residue from Senecio brasiliensis affects behavior and striatal neurotransmitter levels of rats in …
Pyrrolizidine alkaloids (PAs) are toxins that are exclusively biosynthesized by plants and are
commonly present in foods and herbs. PAs are usually associated with poisoning events in
livestock and human beings. The aim of the present study was to evaluate the behavioral
and neurochemical effects of prenatal exposure to PA integerrimine N-oxide of rats in
adulthood. Pregnant Wistar rats received integerrimine N-oxide from the butanolic residue of
Senecio brasiliensis by gavage on gestational days 6–20 at doses of 3, 6 and 9 mg/kg …
commonly present in foods and herbs. PAs are usually associated with poisoning events in
livestock and human beings. The aim of the present study was to evaluate the behavioral
and neurochemical effects of prenatal exposure to PA integerrimine N-oxide of rats in
adulthood. Pregnant Wistar rats received integerrimine N-oxide from the butanolic residue of
Senecio brasiliensis by gavage on gestational days 6–20 at doses of 3, 6 and 9 mg/kg …
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