Triangular silver nanoplates (TSNPs) may find application in next generation optical bio-sensors owing to the high sensitivity of the spectral position of their main plasmon band to changes in local refractive index. Unfortunately, etching of the anisotropic nanoplates to spherical particles occurs upon exposure to chloride ions from salt, with a concomitant decrease in optical sensitivity. Herein are detailed two general methods for the silica coating of TSNPs, with the aim of forming a protective barrier against chloride etching. It has been necessary to modify literature approaches for the coating of spherical Ag nanoparticles, since these are either ineffective for anisotropic nanoplates or lead to their degradation. The first method is a modified Stöber approach using tetraethylorthosilicate (TEOS) as the alkoxide precursor and dimethylamine in low concentration as the basic catalyst, with prior priming of the nanoplate surfaces by diaminopropane. The thickness of the silica layer can be tuned between 7 and 20 nm by varying the primer and alkoxide concentrations. The second method involves deposition of a thin dense layer of silica from sodium silicate solution onto mercaptopropyltriethoxysilane (MPTES) or mercaptopropyltrimethoxysilane (MPTMS) primed TSNPs. This latter method offers protection against anion etching – experiments suggest that the adsorbed MPTES provides much of the barrier to chloride ions, while the silica shell serves to prevent particle aggregation. It was found that the silica coated particles substantially retained the sensitivity to refractive index of the as-grown TSNPs while being able to withstand salt concentrations typical of bio-testing conditions.