Prevalence of Epstein-Barr viral sequences and EBV LMP1 oncogene deletions in Burkitt's lymphoma from Pakistan: epidemiological correlations
A Mansoor, MS Stevenson, RZ Li, K Frekko, W Weiss… - Human pathology, 1997 - Elsevier
To investigate the potential relationship of socioeconomic status with the prevalence of
Epstein-Barr virus (EBV) and to understand the significance of del-LMP-1 within EBV+ cases
of Burkitt's lymphoma (BL), we studied 10 cases of BL, 30 cases of diffuse large cell
lymphoma (DLCL) arising in nonimmunocompromised patients, and 30 reactive tonsillar
biopsy specimens from Pakistan. Each lymphoma was analyzed for EBV by EBER1 RNA in
situ hybridization (EBV-RISH). Cases showing hybridization signal within neoplastic cells …
Epstein-Barr virus (EBV) and to understand the significance of del-LMP-1 within EBV+ cases
of Burkitt's lymphoma (BL), we studied 10 cases of BL, 30 cases of diffuse large cell
lymphoma (DLCL) arising in nonimmunocompromised patients, and 30 reactive tonsillar
biopsy specimens from Pakistan. Each lymphoma was analyzed for EBV by EBER1 RNA in
situ hybridization (EBV-RISH). Cases showing hybridization signal within neoplastic cells …
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