Prevention of central venous catheter-associated thrombosis: a meta-analysis

A Kirkpatrick, S Rathbun, T Whitsett… - The American journal of …, 2007 - Elsevier
PURPOSE: Anticoagulant prophylaxis in patients with central venous catheters is
controversial. We performed a meta-analysis of randomized controlled trials of anticoagulant
prophylaxis in patients with central venous catheters. METHODS: MEDLINE and EMBASE
were searched up to May 2006, supplemented by manual searches of conference
proceedings and bibliographies. RESULTS: Fifteen trials were included. Unfractionated
heparin infusion, oral fixed low-dose vitamin K antagonist, and subcutaneous low-molecular …
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