Primary cutaneous peripheral T-cell lymphoma, not otherwise specified with mammalian target of rapamycin mutation: A novel finding for targeted treatment
C De la Sancha, C Burgin, S Warren… - JAAD Case …, 2020 - jaadcasereports.org
… Primary cutaneous peripheral T-cell lymphoma, not otherwise specified (pcPTCL-NOS) is
a rare, progressive, and often fatal disease with no specific treatment regimen that presents
as rapidly enlarging plaques or nodules. Here, we present a case of progressive pcPTCL-NOS
with mammalian target of rapamycin (mTOR) mutation and variable T-cell antigen
expression. mTOR mutation in pcPTCL-NOS may represent a new therapeutic target. …
a rare, progressive, and often fatal disease with no specific treatment regimen that presents
as rapidly enlarging plaques or nodules. Here, we present a case of progressive pcPTCL-NOS
with mammalian target of rapamycin (mTOR) mutation and variable T-cell antigen
expression. mTOR mutation in pcPTCL-NOS may represent a new therapeutic target. …