The main goals of wire electrical discharge machining (WEDM) manufacturers and users are to achieve a better stability and high productivity of the manufacturing process. The investigation on machinability of Aluminium Matrix Composite (AMC) using Wire-cut Electric Discharge Machining (WEDM) machine is constructed. The aim of this project to determine the most optimum machining parameter that will be increased the machinability of AMC based on material removal rate (MRR). A series of experiments have been performed on AMC reinforced 5% alumina (Al2O3) with dimension 100mm x 3 mm x 4 mm. The test specimens have been cut by using different machining parameter combinations on the Sodick AQ327L WEDM machine in the Teaching Factory of Universiti Malaysia Perlis (UniMAP). The Full Factorial Design of Experiment approach with two levels was used to determine the combination of machining parameter based on Pulse-off time (µs), Servo Voltage (V), and Wire Tension (gf/mm). The result of calculated MRR was analyzed using Regression Analysis Method to determine the mathematical model between machining parameter and machining characteristics.