Pro-inflammatory cytokines are associated with podocyte damage and proximal tubular dysfunction in the early stage of diabetic kidney disease in type 2 diabetes …
O Milas, F Gadalean, A Vlad, V Dumitrascu… - Journal of Diabetes and …, 2020 - Elsevier
Aims To evaluate if there is a link between inflammation (expressed by inflammatory
cytokines) and the early stage of diabetic kidney disease (DKD), as shown by markers of
podocyte damage and proximal tubular (PT) dysfunction. Methods In this study were
enrolled 117 type 2 DM patients (36-normoalbuminuria, 42-microalbuminuria, 39-
macroalbuminuria), and 11 healthy subjects. Serum and urinary IL-1 alpha, IL-8, IL-18,
urinary albumin: creatinine ratio (UACR), eGFR, biomarkers of podocyte damage …
cytokines) and the early stage of diabetic kidney disease (DKD), as shown by markers of
podocyte damage and proximal tubular (PT) dysfunction. Methods In this study were
enrolled 117 type 2 DM patients (36-normoalbuminuria, 42-microalbuminuria, 39-
macroalbuminuria), and 11 healthy subjects. Serum and urinary IL-1 alpha, IL-8, IL-18,
urinary albumin: creatinine ratio (UACR), eGFR, biomarkers of podocyte damage …
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