Pro-inflammatory potential of wood smoke and traffic-derived particles in a monocytic cell line
A Kocbach, E Namork, PE Schwarze - Toxicology, 2008 - Elsevier
Lung inflammation is an important process in host defence to inhaled particulate matter. To
what extent physicochemical properties of particles from different sources influence their
inflammatory potential has not been fully clarified. The aim of this study was to investigate
the potential of particles from wood smoke and traffic to induce a release of pro-inflammatory
cytokines in the monocytic cell line THP-1. The influence of endotoxin on cytokine release
was investigated using the inhibitor polymyxin B sulphate, whereas the responses to native …
what extent physicochemical properties of particles from different sources influence their
inflammatory potential has not been fully clarified. The aim of this study was to investigate
the potential of particles from wood smoke and traffic to induce a release of pro-inflammatory
cytokines in the monocytic cell line THP-1. The influence of endotoxin on cytokine release
was investigated using the inhibitor polymyxin B sulphate, whereas the responses to native …
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