[HTML][HTML] Probiotic Lactobacillus plantarum IS 10506 supplementation increase SCFA of women with functional constipation

PD Kusumo, H Maulahela, AP Utari… - Iranian Journal of …, 2019 - ncbi.nlm.nih.gov
Iranian Journal of Microbiology, 2019ncbi.nlm.nih.gov
Materials and Methods: Randomized Double-Blind Controlled Trial (RCT) was conducted on
women with functional constipation (n= 37) in the community of Jakarta and profile of SCFA
was assessed by using GC-MS from the stool after 21 days supplementation of fermented
milk (placebo and probiotic). Results: Probiotic supplementation significantly influenced
acetate titer (p= 0,032) marginally significant for propionate and butyrate (p= 0.063 and p=
0.068, respectively) and the respondent with increasing SCFA's metabolite are higher in …
Materials and Methods:
Randomized Double-Blind Controlled Trial (RCT) was conducted on women with functional constipation (n= 37) in the community of Jakarta and profile of SCFA was assessed by using GC-MS from the stool after 21 days supplementation of fermented milk (placebo and probiotic).
Results:
Probiotic supplementation significantly influenced acetate titer (p= 0,032) marginally significant for propionate and butyrate (p= 0.063 and p= 0.068, respectively) and the respondent with increasing SCFA’s metabolite are higher in probiotic group compared to the respondents in placebo group. Acetate is the highest SCFA titer found in faeces samples of women with functional constipation.
Conclusion:
Probiotic Lactobacillus plantarum IS 10506 supplementation influenced all the SCFA parameter (acetate, propionate and butyrate).
ncbi.nlm.nih.gov
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