[HTML][HTML] Probiotic bacteria attenuates cisplatin-induced nephrotoxicity through modulation of oxidative stress, inflammation and apoptosis in rats
Objective: To investigate the effects of probiotic bacteria on cisplatin (CP)-induced
nephrotoxicity. Methods: In the present study, 50 Sprague-Dawley rats were used and
randomly divided into five groups including control, CP, probiotic bacteria treatment groups
with different doses (0.5 and 1 mL) and only probiotic bacteria group. After CP and probiotic
administration on seven days, rats sacrificed under anesthesia on the eighth day. The serum
urea, creatinine, and blood urea nitrogen levels were analyzed. In renal tissue …
nephrotoxicity. Methods: In the present study, 50 Sprague-Dawley rats were used and
randomly divided into five groups including control, CP, probiotic bacteria treatment groups
with different doses (0.5 and 1 mL) and only probiotic bacteria group. After CP and probiotic
administration on seven days, rats sacrificed under anesthesia on the eighth day. The serum
urea, creatinine, and blood urea nitrogen levels were analyzed. In renal tissue …
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