Production of antimicrobial peptides is preserved in aging

JE Castañeda-Delgado, NY Miranda-Castro… - Clinical …, 2013 - Elsevier
There is an increased susceptibility to infections during elderly, mainly because of the
decreased efficacy of adaptive immunity to contain microorganisms. Albeit most of the
elderly adults develop this deficiency in adaptive immunity only a minor percentage of them
developed recurrent infectious diseases, thus innate immunity represents an important
barrier to avoid infections in this group of aged people. Since antimicrobial peptides are
important molecules of innate immunity in the study we sought to determine whether healthy …
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