过去一年中添加的文章,按日期排序

[HTML][HTML] Hypomethylation of the RUNX2 Gene Is a New Potential Biomarker of Primary Osteoporosis in Men and Women

B Yalaev, A Tyurin, K Akhiiarova… - International Journal of …, 2024 - mdpi.com
7 天前 - profile from a pool of peripheral blood cells in men and women over 50 years of age
of … as a factor in epigenetic induction to maintain and preserve cellular identity after mitosis …

Reorganization of H3K9me heterochromatin leads the neuronal impairment via the cascading destruction of KDM3B-centered epigenomic network

MJ An, JY Kim, J Kim, DH Kim, GS Shin, HM Lee… - iScience, 2024 - Elsevier
13 天前 - … in differentiated cells is unclear. Here, we examine age-dependent transcriptomic
profiling of terminally differentiated mouse retina to identify epigenetic regulators involved in …

Single-cell RNA sequencing analysis revealed rod photoreceptors are most sensitive to age-induced degeneration

M Chen, M Tang, B Zou, H Xu - … Ophthalmology & Visual …, 2024 - iovs.arvojournals.org
23 天前 - … of retinal cells and their gene expression profiles. Methods : Single-cell RNA sequencing
age-related degeneration due to epigenetic modifications and metabolic alternations. …

Single-nuclei multiomics meta-analysis of human organoids and fetal retina reveals developmental transcriptional and epigenetic differences

J Li, Z Zuo, S Ferdous, X Qian, Y Li… - … & Visual Science, 2024 - iovs.arvojournals.org
23 天前 - … of gene expression profiles, transcriptional trajectories… age and retinal organoid
samples from 5- and 45-weeks were collected and subjected to single nuclei multiome profiling

Spindle cell lesions with oncogenic EGFR kinase domain aberrations: expanding the spectrum of protein kinase-related mesenchymal tumors

S Vallese, S Barresi, L Hiemcke-Jiwa, S Patrizi… - Modern Pathology, 2024 - Elsevier
26 天前 - … The flat profile reflects the benign clinical course of our cases. … DNA methylation
profiling demonstrates an epigenetic relationship. It can be of help in their diagnosis and …

Superficial Neurocristic EWSR1:: FLI1 Fusion Tumor: A Distinctive, Clinically Indolent, S100 Protein/SOX10-Positive Neoplasm

AL Folpe, MT Tetzlaff, SD Billings, J Torres-Mora… - Modern Pathology, 2024 - Elsevier
30 天前 - … , a tumor that epigenetically segregates from conventional … and single cells resembling
those seen in the cell nests, … subjected to DNA methylation profiling and then compared …

Preterm birth and the early-life respiratory microbiota: implications for host epigenetics and respiratory health

JM Binkowska - 2024 - era.ed.ac.uk
37 天前 - profiles further support this conclusion. This work thus suggests that host epigenetics
may … as between the microbiota and host epigenetics. These observations warrant further …

[HTML][HTML] Individual longitudinal changes in DNA-methylome identify signatures of early-life adversity and correlate with later outcome.

AK Short, R Weber, N Kamei, CW Thai, H Arora… - Neurobiology of …, 2024 - Elsevier
40 天前 - … predict vulnerability to ELA consequences in an individual child. Epigenetic markers
including peripheral-cell DNA-methylation profiles may encode ELA and provide predictive …

Integrated Molecular and Histopathological Studies of Testicular Germ Cell Tumor Biology

N Mehta - 2024 - dash.lib.harvard.edu
40 天前 - … -stained whole slide images, single-cell RNA-sequencing, and orthogonal epigenetic
profiling data to both investigate transcriptional and epigenetic modes of TGCT subtype …

A roadmap to human hippocampal neurogenesis in adulthood, aging and AD.

O Lazarov, A Disouky, M Sanborn, M Mostafa… - 2024 - researchsquare.com
41 天前 - … Together, our data implies that rst, a concerted action of transcription and epigenetic
… to or from each individual cell type by neuronal ligands was lower in selected cell types, ie, …