Prognostic and predictive value of histogram analysis in patients with non-small cell lung cancer refractory to platinum treated by nivolumab: a multicentre …

M Ravanelli, GM Agazzi, G Milanese, E Roca… - European Journal of …, 2019 - Elsevier
Purpose The aim of this study was to assess computed-tomography histogram analysis
(CTHA) as prognostic and predictive factor in platinum-refractory non-small cell lung
carcinoma (NSCLC) treated with immune checkpoint inhibitor Nivolumab. Method One
hundred and four patients were enrolled from 3 different centers. CT was performed using
similar parameters among different scanners. CTHA was performed with the proprietary
software TexRAD, which extracts histogram features at different spatial scale (spatial scale …
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