Diabetes associated gastrointestinal complications have more common as the rate of diabetes has increased. The present study was undertaken to investigate, prokinetic effect of Hyponidd, a herbomineral formulation (HMF) in streptozotocin induced diabetic rats. Diabetes was induced by single intraperitoneal administration of STZ (55 mg kg^-1) in rats. The diabetic rats, after receiving two weeks of drug treatment were screened for Gastric Emptying (GE), Intestinal Transit (IT) and in vitro study of distal colonic smooth muscle. Two weeks of treatment with HMF (100 and 200 mg kg^-1 p.o.) in diabetic rats showed significant restoration of impaired gastric emptying and intestinal transit. Furthermore, there was a significant decrease in EC₅₀ on rat colon. Therefore, it may be concluded that Hyponidd exert prokinetic effect and has therapeutic potential in diabetic gastroparesis and related gastrointestinal impairments.