Prolonged and extended impacts of SARS-CoV-2 on the olfactory neurocircuit

M Kishimoto-Urata, S Urata, R Kagoya, F Imamura… - Scientific reports, 2022 - nature.com
… While the damaged OE is gradually restored 4 and olfactory function is … well as chronic
olfactory dysfunction in some cases 6 . This study examined the long-term effects of SARS-CoV-2

Prolonged and extended impacts of SARS-CoV-2 on the olfactory neurocircuit

S Paessler, M Kishimoto-Urata, S Urata, R Kagoya… - 2022 - researchsquare.com
… 28 and desquamation of the entire OE, including olfactory sensory neurons (OSNs)3. …
chronic olfactory dysfunction in some cases5. This study examined the effects 32 of SARS-CoV-2

Neuroinvasion and anosmia are independent phenomena upon infection with SARS-CoV-2 and its variants

GD de Melo, V Perraud, F Alvarez… - Nature …, 2023 - nature.com
… Other authors reported persistent microgliosis in the olfactory … an impaired olfactory
performance (ie longer time to find the … aimed to assess the effect of infection on the olfactory

Mechanisms of SARS-CoV-2-associated anosmia

T Tsukahara, DH Brann, SR Datta - Physiological Reviews, 2023 - journals.physiology.org
Prolonged and 411 extended impacts of SARS-CoV-2 on the olfactory neurocircuit. Scientific
Reports 12, 5728. 412 Kohli, P., Soler, ZM, Nguyen, SA, Muus, JS, and Schlosser, RJ (2016…

Olfactory dysfunction in COVID-19: new insights into the underlying mechanisms

R Butowt, K Bilinska, CS von Bartheld - Trends in Neurosciences, 2023 - cell.com
… From a historical perspective, the impact of SARS-CoV-2 on olfaction appears to be … The
SUS extends throughout the olfactory epithelium, with its basal process reaching the basal …

[HTML][HTML] The Influence of Microglia on Neuroplasticity and Long-Term Cognitive Sequelae in Long COVID: Impacts on Brain Development and Beyond

LS Chagas, CA Serfaty - International Journal of Molecular Sciences, 2024 - mdpi.com
impact of SARS-CoV-2 infection on the olfactory pathway observed an incomplete recovery
of sensory neurons, prolonged glial activation in the olfactory … and neural circuit formation, …

Effects of nasal inflammation on the olfactory bulb

BJ LaFever, F Imamura - Journal of neuroinflammation, 2022 - Springer
… case of SARS-CoV-2 infection. This review summarizes the … B, C OB neurocircuitry following
challenge of chronic nasal … olfactory deficits for long periods of time as a result of chronic

[HTML][HTML] Early corticosteroid treatment enhances recovery from SARS-CoV-2 induced loss of smell in hamster

L Merle-Nguyen, O Ando-Grard, C Bourgon… - Brain, Behavior, and …, 2024 - Elsevier
… In this study, we explored its impact using hamster as an … Our results indicate that persistent
inflammation of the olfactory … a long-term persistence of inflammation in the olfactory system …

Mechanism and treatment of olfactory dysfunction caused by coronavirus disease 2019

B Hu, M Gong, Y Xiang, S Qu, H Zhu, D Ye - Journal of Translational …, 2023 - Springer
… coronavirus 2 (SARS-CoV-2) has had negative impacts on public … neural circuit. Analysis
of imaging revealed that the OB … , SARS-CoV-2 may cause long-term damage to the olfactory

Oral SARS-CoV-2 inoculation causes nasal viral infection leading to olfactory bulb infection: an experimental study

R Ueha, T Ito, R Furukawa, M Kitabatake… - Frontiers in cellular …, 2022 - frontiersin.org
… The other study using Syrian golden hamsters reported prolonged and extended impacts of
SARS-CoV-2 on the olfactory neurocircuit such as prolonged activation of glial cells in the OB…