Promoting cardiac repair through simple engineering of nanoparticles with exclusive targeting capability toward myocardial reperfusion injury by thermal resistant …

Z Liu, W Lian, Q Long, R Cheng… - Advanced Functional …, 2022 - Wiley Online Library
Nanoparticle (NP)‐based intravenous administration represents the most convenient
cardiac targeting delivery routine, yet, there are still therapeutic issues due to the lack of
targeting efficiency and specificity. Active targeting methods using functionalization of
ligands onto the NPs' surface may be limited by trivial modification procedures and reduced
targeting yield in vivo. Here, a microfluidics assisted single step, green synthesis method is
introduced for producing targeting ligands free heart homing NPs in a tailored manner. The …

Promoting Cardiac Repair through Simple Engineering of Nanoparticles with Exclusive Targeting Capability toward Myocardial Reperfusion Injury by Thermal …

Z Liu, W Lian, Q Long, R Cheng… - Advanced Functional …, 2022 - Wiley Online Library
In article number 2204666, Qiang Zhao, Xiaofeng Ye, Xianming Deng, Hélder A. Santos,
and co-workers introduce a microfluidics-assisted single step, green synthesis method for
producing targeting ligands free heart homing nanoparticles in a tailored manner. The
developed microfluidic platform facilitates an economically feasible and simple yet robust
synthesis procedure for nanoparticle production, which shows great clinical translational
potential as an alternative post-conditioning routine after revascularization surgery.
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