Protective potency of Astragalus polysaccharides against tilmicosin-induced cardiac injury via targeting oxidative stress and cell apoptosis-encoding pathways in rat
Tilmicosin (Til) was purposed to be used in the treatment of a wide range of respiratory
diseases in livestock. However, undesirable adverse effects, cardiac toxicity, in particular,
may be associated with Til therapy. In the present study, the response of adult rats
administered Til subcutaneously at different doses (10, 25, 50, 75, and 100 mg/kg bw; single
injection) was evaluated. Astragalus polysaccharide (AP) at two doses (100 and 200 mg/kg
bw; intraperitoneally) was investigated for its potential to counteract the cardiac influences …
diseases in livestock. However, undesirable adverse effects, cardiac toxicity, in particular,
may be associated with Til therapy. In the present study, the response of adult rats
administered Til subcutaneously at different doses (10, 25, 50, 75, and 100 mg/kg bw; single
injection) was evaluated. Astragalus polysaccharide (AP) at two doses (100 and 200 mg/kg
bw; intraperitoneally) was investigated for its potential to counteract the cardiac influences …
Protective potency of Astragalus polysaccharides against tilmicosin-induced cardiac injury via targeting oxidative stress and cell apoptosis-encoding pathways in rat
SRE Khallil - springer, 2020 - publications.zu.edu.eg
Tilmicosin (Til) was purposed to be used in the treatment of a wide range of respiratory
diseases in livestock. However, undesirable adverse effects, cardiac toxicity, in particular,
may be associated with Til therapy. In the present study, the response of adult rats
administered Til subcutaneously at different doses (10, 25, 50, 75, and 100 mg/kg bw; single
injection) was evaluated. Astragalus polysaccharide (AP) at two doses (100 and 200 mg/kg
bw; intraperitoneally) was investigated for its potential to counteract the cardiac influences …
diseases in livestock. However, undesirable adverse effects, cardiac toxicity, in particular,
may be associated with Til therapy. In the present study, the response of adult rats
administered Til subcutaneously at different doses (10, 25, 50, 75, and 100 mg/kg bw; single
injection) was evaluated. Astragalus polysaccharide (AP) at two doses (100 and 200 mg/kg
bw; intraperitoneally) was investigated for its potential to counteract the cardiac influences …
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