Protective role of renal proximal tubular alpha-synuclein in the pathogenesis of kidney fibrosis

M Bozic, M Caus, RR Rodrigues-Diez… - Nature …, 2020 - nature.com
… ; however, there was no correlation between the tubular … loss of tubular SNCA expression
and declining renal function … the potential role of renal proximal tubule SNCA in kidney fibrosis, …

[PDF][PDF] Protective role of renal proximal tubular alpha-synuclein in the pathogenesis of kidney fibrosis

M Bozic, M Caus Enríquez, R Rodrigues-Diez… - 2020 - repositori.udl.cat
… ; however, there was no correlation between the tubular … loss of tubular SNCA expression
and declining renal function … the potential role of renal proximal tubule SNCA in kidney fibrosis, …

FP331 ALPHA-SYNUCLEIN MAINTAINS THE EPITHELIAL PHENOTYPE AND PROTECTS FROM RENAL FIBROSIS

M Bozic, M Caus, RR Rodrigues-Diez… - Nephrology Dialysis …, 2019 - academic.oup.com
… , but whether it has a protective role in the kidney is unknown. The aim … renal proximal
tubular epithelial cells (RPTECs) and its role in the pathogenesis of renal tubulointerstitial fibrosis. …

New insights into the pathogenesis of diabetic nephropathy: proximal renal tubules are primary target of oxidative stress in diabetic kidney

R Haraguchi, Y Kohara, K Matsubayashi… - Acta histochemica et …, 2020 - jstage.jst.go.jp
… Our findings indicate that proximal tubular defects are the initial … , and that controlling renal
tubular damage could be an effective … Moreover, proximal renal tubules play a protective role

New therapeutic targets in chronic kidney disease progression and renal fibrosis

S Rayego-Mateos, JM Valdivielso - Expert Opinion on Therapeutic …, 2020 - Taylor & Francis
… the proximal tubule (S2/S3) and in the early (S1) proximal tubule, … major pathogenic and
aggravating factor for kidney disease, … our laboratory has shown a protective effect of the protein-…

Protein DJ-1 and its anti-oxidative stress function play an important role in renal cell mediated response to profibrotic agents

M Eltoweissy, GH Dihazi, GA Müller, AR Asif… - Molecular …, 2016 - pubs.rsc.org
… of DJ-1 in the proximal tubule of the Col4a3 mice compared … ) treated renal cell models and
the observed protective role of … in cooperation with Hsp70 against alpha-synuclein toxicity in …

… AND EXTRA-TERMINAL (BET) PROTEIN INHIBITOR, REDUCES SERUM FGF23 IN CARDIOVASCULAR DISEASE AND CHRONIC KIDNEY DISEASE PATIENTS

K Kalantar-Zadeh, C Zoccali, S Beddhu… - Nephrology Dialysis …, 2019 - academic.oup.com
… , but whether it has a protective role in the kidney is unknown. The aim … renal proximal
tubular epithelial cells (RPTECs) and its role in the pathogenesis of renal tubulointerstitial fibrosis. …

… DAMAGE BY PHOSPHORUS LOADING ACCELERATES THE PROGRESSION OF CKD MODEL BY THE ACCUMULATION OF MINOR KIDNEY INJURY IN KLOTHO …

K Tsuchiya, H Sugiura, N Hanafusa… - Nephrology Dialysis …, 2019 - academic.oup.com
… , but whether it has a protective role in the kidney is unknown. The aim … renal proximal
tubular epithelial cells (RPTECs) and its role in the pathogenesis of renal tubulointerstitial fibrosis. …

Metabolic reprogramming and renal fibrosis

X Zhu, L Jiang, M Long, X Wei, Y Hou, Y Du - Frontiers in medicine, 2021 - frontiersin.org
… of chronic kidney disease, but all of these patients have renal fibrosis. … treatment of fibrosis
of the kidneys and other organs. Figure 1 summarizes the metabolism in renal proximal tubule

Protective effects of carnosol on renal interstitial fibrosis in a murine model of unilateral ureteral obstruction

JH Park, J Leem, SJ Lee - Antioxidants, 2022 - mdpi.com
Renal fibrosis is a common feature of chronic kidney disease … border of proximal tubules,
and interstitial fibrosis. These … that CS treatment ameliorates renal injury and fibrosis in the …