This study evaluated the quality of oil extracted from catfish and mackerel in comparison with what obtains in commercial cod liver oil. Oil were extracted from two common fishes in Africa (Catfish and Meckerel) and analyzed for Proximate, Physical, Chemical and Mineral contents using standard methods. The fatty acid profiles were also determined with the use of Gas chromatography, while the sensory properties were determined through the use of a 10 man panel. Results revealed from the analysis conducted that there was no significant difference at P< 0.05 between the values of the oil extracted from Catfish, Meckerel and the commercial available Codliver oil in majority of the parameters determined. The rate of poverty in most part of Africa makes the diet taken inadequate in terms of nutrition, there is need to take in supplements in order to cater for the deficiencies in the diet. Since Codliver oil which is taken as a food supplements can still not be affordable by some, it is imperative to seek out alternatives. Therefore the oil from Catfish and Meckerel can be used as alternative to Codliver oil.