RNA polymerase I transcription and pre-rRNA processing are linked by specific SSU processome components
JEG Gallagher, DA Dunbar, S Granneman… - Genes & …, 2004 - genesdev.cshlp.org
Sequential events in macromolecular biosynthesis are often elegantly coordinated. The
small ribosomal subunit (SSU) processome is a large ribonucleoprotein (RNP) required for
processing of precursors to the small subunit RNA, the 18S, of the ribosome. We have found
that a subcomplex of SSU processome proteins, the t-Utps, is also required for optimal rRNA
transcription in vivo in the yeast Saccharomyces cerevisiae. The t-Utps are ribosomal
chromatin (r-chromatin)-associated, and they exist in a complex in the absence of the U3 …
small ribosomal subunit (SSU) processome is a large ribonucleoprotein (RNP) required for
processing of precursors to the small subunit RNA, the 18S, of the ribosome. We have found
that a subcomplex of SSU processome proteins, the t-Utps, is also required for optimal rRNA
transcription in vivo in the yeast Saccharomyces cerevisiae. The t-Utps are ribosomal
chromatin (r-chromatin)-associated, and they exist in a complex in the absence of the U3 …
[PDF][PDF] RNA polymerase I transcription and pre-rRNA processing are linked
JEG Gallagher, DA Dunbar, S Granneman - researchgate.net
Sequential events in macromolecular biosynthesis are often elegantly coordinated. The
small ribosomal subunit (SSU) processome is a large ribonucleoprotein (RNP) required for
processing of precursors to the small subunit RNA, the 18S, of the ribosome. We have found
that a subcomplex of SSU processome proteins, the t-Utps, is also required for optimal rRNA
transcription in vivo in the yeast Saccharomyces cerevisiae. The t-Utps are ribosomal
chromatin (r-chromatin)-associated, and they exist in a complex in the absence of the U3 …
small ribosomal subunit (SSU) processome is a large ribonucleoprotein (RNP) required for
processing of precursors to the small subunit RNA, the 18S, of the ribosome. We have found
that a subcomplex of SSU processome proteins, the t-Utps, is also required for optimal rRNA
transcription in vivo in the yeast Saccharomyces cerevisiae. The t-Utps are ribosomal
chromatin (r-chromatin)-associated, and they exist in a complex in the absence of the U3 …
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