Rab6 and myosin II at the cutting edge of membrane fission
Nature cell biology, 2010•nature.com
Rab GTPases regulate the dynamics of transport carriers by participating in their
translocation across the cytoplasm, and in their docking and fusion with acceptor
compartments. An interaction between Golgi-associated Rab6 and myosin II has now been
shown to regulate the fission of Rab6-positive carriers, illuminating a previously
unappreciated role for Rab6 and the actomyosin system in carrier biogenesis.
translocation across the cytoplasm, and in their docking and fusion with acceptor
compartments. An interaction between Golgi-associated Rab6 and myosin II has now been
shown to regulate the fission of Rab6-positive carriers, illuminating a previously
unappreciated role for Rab6 and the actomyosin system in carrier biogenesis.
Rab GTPases regulate the dynamics of transport carriers by participating in their translocation across the cytoplasm, and in their docking and fusion with acceptor compartments. An interaction between Golgi-associated Rab6 and myosin II has now been shown to regulate the fission of Rab6-positive carriers, illuminating a previously unappreciated role for Rab6 and the actomyosin system in carrier biogenesis.
nature.com
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