Reaction-based two-photon probes for in vitro analysis and cellular imaging of monoamine oxidase activity

D Kim, S Sambasivan, H Nam, KH Kim… - Chemical …, 2012 - pubs.rsc.org
D Kim, S Sambasivan, H Nam, KH Kim, JY Kim, T Joo, KH Lee, KT Kim, KH Ahn
Chemical Communications, 2012pubs.rsc.org
Reaction-based fluorescent probes for monoamine oxidases A and B are developed based
on a new two-photon absorbing compound and its precursor. The probes show turn-on
fluorescence response to the enzymes owing to the two-photon absorbing compound
produced by the enzymatic activity, as monitored by one-as well as two-photon microscopy
for the first time.
Reaction-based fluorescent probes for monoamine oxidases A and B are developed based on a new two-photon absorbing compound and its precursor. The probes show turn-on fluorescence response to the enzymes owing to the two-photon absorbing compound produced by the enzymatic activity, as monitored by one- as well as two-photon microscopy for the first time.
The Royal Society of Chemistry
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