Reactive oxygen species in the immune system

Y Yang, AV Bazhin, J Werner… - International reviews of …, 2013 - Taylor & Francis
… of the immune response, such as host defense, immune cells' interaction and activation,
and immune suppression. Upon pathogen encounter, our immune system has developed a …

The influence of reactive oxygen species in the immune system and pathogenesis of multiple sclerosis

M Tavassolifar, M Vodjgani, Z Salehi… - Autoimmune …, 2020 - Wiley Online Library
… Multiple roles have been indicated for reactive oxygen species (ROS) in the immune system
in recent years. ROS have been extensively studied due to their ability to damage DNA and …

Reactive oxygen species and immune regulation

Z Yang, Z Min, B Yu - International Reviews of Immunology, 2020 - Taylor & Francis
Reactive oxygen species (ROS) is a kind of single electron reduction product of oxygen in
vivo. … In fact, ROS plays an important role in the immune system of the body, participates in the …

Reactive oxygen species regulate T cell immune response in the tumor microenvironment

X Chen, M Song, B Zhang… - Oxidative Medicine and …, 2016 - Wiley Online Library
Reactive oxygen species (ROS) produced by cellular metabolism play an important role as
signaling messengers in immune system. ROS elevated in the tumor microenvironment are …

Harnessing immune response using reactive oxygen Species-Generating/Eliminating inorganic biomaterials for disease treatment

C Zhao, H Deng, X Chen - Advanced Drug Delivery Reviews, 2022 - Elsevier
… functions mediated by reactive oxygen species (ROS) in the immune system, a number of …
host immunity to maximize the therapeutic potency by eliciting a favorable immune response. …

Are reactive oxygen species always detrimental to pathogens?

CN Paiva, MT Bozza - Antioxidants & redox signaling, 2014 - liebertpub.com
… Reactive oxygen species (ROS) are used by the immune system as weapons against
pathogens; however, antioxidants have long been recognized as protectors of host organism …

Spatial properties of reactive oxygen species govern pathogen-specific immune system responses

EE To, JJ O'Leary, LAJ O'Neill, R Vlahos… - Antioxidants & redox …, 2020 - liebertpub.com
… Significance: Reactive oxygen species (ROS) are often … paradigm that these reactive species
are not generated … this has important consequences for immune system function. Currently, …

COVID-19: captures iron and generates reactive oxygen species to damage the human immune system

L Wenzhong, L Hualan - Autoimmunity, 2021 - Taylor & Francis
… Briefly, the virus inhibited the immune system through “ROS escape”, and damaged the
immune system by “ROS attack”. The destruction instigated a strong cytokine storm, leading to …

Roles of reactive oxygen species in cell signaling pathways and immune responses to viral infections

Z Li, X Xu, X Leng, M He, J Wang, S Cheng, H Wu - Archives of virology, 2017 - Springer
… , dysfunction of the immune system, apoptosis or cell death [42]. Since the 1960s, when
reactive oxygen species were first described, we have known that oxygen could both support …

Abundance of reactive oxygen species (ROS) is associated with tumor aggressiveness, immune response, and worse survival in breast cancer

M Oshi, S Gandhi, L Yan, Y Tokumaru, R Wu… - Breast cancer research …, 2022 - Springer
Reactive oxygen species (ROS) are oxygen-containing molecules that have high
reactivity and play roles in protection or harm the cancer cells. We aimed to clarify the clinical …