Recent advances in the synthesis of carbazoles from indoles

T Aggarwal, AK Verma - Organic & Biomolecular Chemistry, 2019 - pubs.rsc.org
T Aggarwal, AK Verma
Organic & Biomolecular Chemistry, 2019pubs.rsc.org
Carbazoles are privileged nitrogen heterocycles that are present in a wide range of natural
products, pharmaceuticals, and functional materials. Due to their wide application, various
synthetic strategies are available in the literature using substituted amines or indoles as a
substrate. Thus, this review comprehensively highlights the (2015–2019) article that focuses
on the synthesis of carbazoles derived from an indole-template through transition-metal
catalyzed C–H functionalization, metal-free cyclization, three-component reaction, and …
Carbazoles are privileged nitrogen heterocycles that are present in a wide range of natural products, pharmaceuticals, and functional materials. Due to their wide application, various synthetic strategies are available in the literature using substituted amines or indoles as a substrate. Thus, this review comprehensively highlights the (2015–2019) article that focuses on the synthesis of carbazoles derived from an indole-template through transition-metal catalyzed C–H functionalization, metal-free cyclization, three-component reaction, and electrophilic iodocyclizations. The synthetic strategies described in this review provided diversely substituted carbazoles and few of them have profound pharmacological activity.
The Royal Society of Chemistry
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