… categories of cell surface receptors, the tropomyosin-related kinase (Trk) tyrosine kinase
receptors and the p75 neurotrophin receptor (p75NTR). These receptors share no sequence …

… irk tyrosine kinases serve as receptors for target-derived neurotrophins. While the mechanism
by which receptor tyrosine kinases impart intracellular signaling has become well under…

… receptors. This review focuses on the mechanisms responsible for the functional interplay
between the two neurotrophin receptor signaling … of the neurotrophin receptor signaling system…

… receptor arises from the variety of ligands and co-receptors which associate with p75 NTR
and regulate its signaling… P75 NTR promotes survival through interactions with Trk receptors, …

… the neurotrophin signaling pathways known for Trk receptors to … for p75NTR in different
receptor complexes and functions. … on the pan-neurotrophin p75NTR receptor and its interacting …

… acts not only in a linear, independent manner, but can also influence the activity of other
cell surface receptors, either directly or through signaling intermediates. Which step and which …

… binding of the neurotrophin nerve growth factor (NGF) to the Trk receptor. This … signals are
then in turn propagated to other messengers, ultimately leading to differentiation, neurotrophin…

… neurotrophin activates p75 neurotrophin receptor (p75NTR), a member of the tumour necrosis
factor receptor … appeared that these truncated receptors did not directly signal, but instead …

… In addition, all neurotrophins activate the p75 neurotrophin receptor, a member of the tumor
… This chapter will provide an overview of neurotrophin biology, their receptors, and signaling …

… of signaling pathways that are normally only active during development. The p75 neurotrophin
receptor (p75 NTR ) is one such signaling … that p75 NTR signaling contributes to neuronal …