Reconstitution of membrane proteins: a GPCR as an example

AD Goddard, PM Dijkman, RJ Adamson… - Methods in …, 2015 - Elsevier
Membrane proteins are the gatekeepers to the cell and are essential to the function of all
cells, controlling the flow of molecules and information across the cell membrane. Much
effort has been put into the development of systems for studying membrane proteins in
simplified environments that nevertheless mimic their native lipid environment. After isolation
and production of purified membrane proteins in detergent, it is often necessary to
reconstitute them into a lipid structure such as liposome, nanodisc, or lipodisq. Each of these …
以上显示的是最相近的搜索结果。 查看全部搜索结果