Reduced numbers of plasmacytoid dendritic cells in aged blood donors
B Pérez-Cabezas, M Naranjo-Gómez… - Experimental …, 2007 - Elsevier
Dendritic cells (DC) play essential functions in both innate and adaptive immune responses.
Peripheral blood DCs are divided into two major subsets, named conventional DC (cDC)
and plasmacytoid DC (pDC), which play specific functions in the immune response. The
absolute numbers of DCs (and their subsets) in peripheral blood may suffer variations due to
physiological or pathological reasons, and therefore the enumeration of DC subsets in blood
samples may be of clinical interest. However, to date this enumeration has produced …
Peripheral blood DCs are divided into two major subsets, named conventional DC (cDC)
and plasmacytoid DC (pDC), which play specific functions in the immune response. The
absolute numbers of DCs (and their subsets) in peripheral blood may suffer variations due to
physiological or pathological reasons, and therefore the enumeration of DC subsets in blood
samples may be of clinical interest. However, to date this enumeration has produced …
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