[HTML][HTML] Reduced-intensity conditioning regimen preserves thymic function in the early period after hematopoietic stem cell transplantation
M Jiménez, C Martínez, G Ercilla, E Carreras… - Experimental …, 2005 - Elsevier
OBJECTIVE: To compare T-cell reconstitution in two groups of patients submitted to
allogeneic stem cell transplantation (SCT): those receiving reduced-intensity conditioning
(RIC, n= 24) and those receiving myeloablative conditioning (MA, n= 27). METHODS: Fifty-
one consecutive patients undergoing SCT were evaluated. Serial assessments of
lymphocyte subsets and T cell receptor excision circles (TRECs) levels were performed
using multiparametric flow cytometry and real-time PCR, respectively. RESULTS: During the …
allogeneic stem cell transplantation (SCT): those receiving reduced-intensity conditioning
(RIC, n= 24) and those receiving myeloablative conditioning (MA, n= 27). METHODS: Fifty-
one consecutive patients undergoing SCT were evaluated. Serial assessments of
lymphocyte subsets and T cell receptor excision circles (TRECs) levels were performed
using multiparametric flow cytometry and real-time PCR, respectively. RESULTS: During the …
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