[HTML][HTML] Regional gray matter volume correlates to physical and mental fatigue in healthy middle-aged adults

HA Putra, K Park, F Yamashita, K Mizuno… - Neuroimage …, 2022 - Elsevier
Previous studies on neural/molecular mechanisms of fatigue focused on a variety of brain
functions, morphological changes, and neurochemical functions such as neurotransmitter
and neuroimmune dynamics. However, MRI morphological changes were adopted primarily
to compare patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
and healthy controls. A few studies have been done on healthy subjects with fatigue scores;
one study with 63 adults (their ages of 53.2±8.3) showed the gray matter volume (GMV) …
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