Regulation of RhoB gene expression during tumorigenesis and aging process and its potential applications in these processes

E Gutierrez, I Cahatol, CAR Bailey, A Lafargue… - Cancers, 2019 - mdpi.com
RhoB loss is an early event during lung tumorigenesis. We … Rhob gene expression during
aging and carcinogenesis in A/… that Rhob protein was decreased in pulmonary tissue with age (…

[PDF][PDF] Regulation of RhoB gene expression during tumorigenesis and aging process and Its potential applications in these processes

CAR Bailey - 2019 - digitalcommons.wustl.edu
RhoB loss is an early event during lung tumorigenesis. We … Rhob gene expression during
aging and carcinogenesis in A/… that Rhob protein was decreased in pulmonary tissue with age (…

Transcriptional and post-transcriptional regulation of the genes encoding the small GTPases RhoA, RhoB, and RhoC: implications for the pathogenesis of human …

E Nomikou, M Livitsanou, C Stournaras… - Cellular and Molecular …, 2018 - Springer
RhoB gene expression indicating the involvement of RhoB in the antimigratory property of
AE in colon cancer cells [… The transcription of the RhoB gene is regulated in a tissue- and age-…

Loss of RhoA promotes skin tumor formation and invasion by upregulation of RhoB

A Garcia-Mariscal, H Li, E Pedersen, K Peyrollier… - Oncogene, 2018 - nature.com
… To investigate whether RhoA gene expression is altered in … a two-stage carcinogenesis
experiment on conditional RhoA … aberrant RhoB levels, we overexpressed RhoB in control cells …

Genetic response to DNA damage: proapoptotic targets of RhoB include modules for p53 response and susceptibility to Alzheimer's disease

U Kamasani, GC Prendergast - Cancer biology & therapy, 2005 - Taylor & Francis
Its potential role in apoptosis has yet to be assessed. As … genes that were strongly
regulated during brain aging were … The possibility that RhoB may influence gene expression

Suppression of rho B expression in invasive carcinoma from head and neck cancer patients

J Adnane, C Muro-Cacho, L Mathews, SM Sebti… - Clinical cancer …, 2002 - AACR
… Thus, it seems that RhoB plays a regulatory role sensing the … whether RhoB expression is
altered in human tumorigenesis… Table 1 also lists the gender, age, status of the patient, RhoB

Rho GTPase signaling in cancer progression and dissemination

E Crosas-Molist, R Samain… - Physiological …, 2022 - journals.physiology.org
… by gene expression and posttranscriptional regulation by … For instance, downregulation
of RHOB expression has been … 2.2), strongly suggest their potential as therapeutic targets in …

[HTML][HTML] A current overview of RhoA, RhoB, and RhoC functions in vascular biology and pathology

R Eckenstaler, M Hauke, RA Benndorf - Biochemical Pharmacology, 2022 - Elsevier
… or function of these proteins plays an important role in the pathogenesis of various cancer
their protein structure is very similar, different mechanisms of regulation of gene expression, …

Rho GTPase function in tumorigenesis

R Karlsson, ED Pedersen, Z Wang… - … (BBA)-Reviews on Cancer, 2009 - Elsevier
… Conceivably, regulation of gene expression and protein degradation controls the … RhoB
came from experiments with adenovirus-mediated ectopic expression of RhoB in ovarian cancer

Rho GTPases modulate malignant transformation of tumor cells

JL Orgaz, C Herraiz, V Sanz-Moreno - Small GTPases, 2014 - Taylor & Francis
… CDK4, and downregulating the mRNA expression of G1 cyclin-… These processes need to
be carefully regulated in order to … cancer model, RhoB promotes tumor angiogenesis through