Relationship between EBV infection and expression of cellular proteins c-Myc, Bcl-2, and Bax in gastric carcinomas
MAP Lima, MVP Ferreira, MAP Barros… - Diagnostic Molecular …, 2008 - journals.lww.com
Background: Epstein-Barr virus (EBV) has been related to tumorigenesis in about 10% of all
gastric carcinomas. Several studies have demonstrated strong evidence of its involvement in
this process, but most of the mechanisms used by the virus to control this process are still
unknown. Previous studies in vitro have indicated a relationship between the virus and
some cellular genes involved in processes such as proliferation and apoptosis. Objective:
The aim of the present study was to investigate a possible EBV-induced tumorigenic …
gastric carcinomas. Several studies have demonstrated strong evidence of its involvement in
this process, but most of the mechanisms used by the virus to control this process are still
unknown. Previous studies in vitro have indicated a relationship between the virus and
some cellular genes involved in processes such as proliferation and apoptosis. Objective:
The aim of the present study was to investigate a possible EBV-induced tumorigenic …
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