Nellore sheep is the tallest mutton breed of sheep in India. This breed was evolved in sub-humid terrain of coastal Andhra. It has made rapid stride into semi-arid Telangana region at the expense of native Deccani sheep, because of farmers' preference for its mutton quality and higher body weight. There is no information available on the performance of Nellore sheep in the semi-arid Telangana, the adopted bastion of the breed. The present study was undertaken on the reproductive performance of Nellore sheep viz., age at first mating of rams, and age at first mating, age at first lambing, lambing interval, lambing%, and twinning% of ewes in the farmers' flocks in three different agro climatic zones of Telangana in Andhra Pradesh, India, viz., Northern Telangana Zone (NTZ), Central Telangana Zone (CTZ), and Southern Telangana Zone (STZ). Climatologically, the annual precipitation of NTZ (1054 mm) is higher than CTZ (995 mm) and STZ (728 mm). The least squares means (µ) along with SEM for various reproductive traits viz., age at first mating of rams, age at first mating of ewes, age at first lambing, lambing interval, lambing%, and twinning% were 586.60±8.29 d, 610.00±3.81 d, 788.39±3.94 d, 420.93±2.76 d, 79.24±0.19%, and 0.22±0.05% respectively. The ewes of NTZ had significantly (P≤0.05) lower lambing interval (414.19±6.63 d) and higher lambing rate (81.78±0.45%) than the other zones. This study implied that Nellore sheep were more prolific in NTZ than the other two zones (CTZ, STZ) of Telangana, thus better suited for comprehensive production.